Potentiating effect of glabridin from Glycyrrhiza glabra on GABA A receptors
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چکیده
منابع مشابه
Potentiating effect of glabridin from Glycyrrhiza glabra on GABAA receptors
Extracts from Glycyrrhiza are traditionally used for the treatment of insomnia and anxiety. Glabridin is one of the main flavonoid compounds from Glycyrrhiza glabra and displays a broad range of biological properties. In the present work, we investigated the effect of glabridin on GABAA receptors. For this purpose, we employed the two-electrode voltage-clamp technique on Xenopus laevis oocytes ...
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Indisputably the third millennium is witnessing the worldwide changes in healthcare. Ayurvedic system of healthcare has gained good popularity. Ayurveda is a profound and comprehensive system of health care that originated in India. This system endeavors to rationalize the all phenomena governing empirical experiences with natural products in medicine. Ayurvedic medicare system has attained pop...
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Glabridin is a major constituent of the root of Glycyrrhiza glabra, which is commonly used in the treatment of cardiovascular and central nervous system diseases. This study aimed to investigate the role of P-glycoprotein (PgP/MDR1) in the intestinal absorption of glabridin. The systemic bioavailability of glabridin was approximately 7.5% in rats, but increased when combined with verapamil. In ...
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This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (nbutanol, ethyl acetate, chloroform and n-hexane) of Glycyrrhiza glabra root. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bacterial strains, i.e P. multocida, E. coli, B. sub...
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Conjunctivitis and its treatment have been widely described in ancient Indian medicine, 50 cases of Conjunctivitis (Acute) were clinically studied with Glycyrrhiza glabra along with comparative approach of Chlorophenicol. 25 cases studied with Glycyrrhiza glabra have shown encouraging results from which the author concludes that, the drug has got a definite role in Conjunctivitis.
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ژورنال
عنوان ژورنال: Biochemistry and Biophysics Reports
سال: 2016
ISSN: 2405-5808
DOI: 10.1016/j.bbrep.2016.04.007